LOUISVILLE, Ky. (AP) -- Chris Redman threw for 397 yards and Lavell Boyd caught a Conference USA-record four touchdown passes as Louisville beat Houston 39-33 Saturday.

Redman was 27-of-53 and tied a season high with five touchdown passes for Louisville (5-3, 2-1 Conference USA). He became the NCAA's career leader in pass attempts late in the first half, breaking the record of 1,530 set by BYU's Ty Detmer from 1988-1991.

Redman, with 1,554 attempts, is six completions short of Detmer's NCAA career completions mark of 958. His 11,605 career passing yards is 3,426 behind Detmer's record 15,031.

Boyd caught 11 passes for 173 yards, including TDs of 7, 18, 25 and 75 yards. Arnold Jackson added nine catches for 119 yards and a 4-yard score.

Ketric Sanford led Houston (4-3, 1-2) with 21 carries for 139 yards, including touchdowns of 5 and 72 yards. Jason McKinley was 20-of-37 for 255 yards and one interception.

The Cardinals, who trailed 24-18 at halftime, took their first lead on Redman's 7-yard pass to Boyd. Following a blocked punt on Houston's next possession, Redman hit Jackson with a 4-yard TD and Louisville led 32-24 with 5:04 remaining in the quarter.

Houston closed to 32-30 on Sanford's 5-yard run but failed on a 2-point conversion that would have tied the game with 2:55 left. Less than a minute later, Redman hit Boyd in the corner of the end zone from 25 yards for a 39-30 lead.

Mike Clark kicked a 35-yard field goal with five seconds to play but the Cougars couldn't convert the ensuing onside kick.