NORMAN, Okla. (AP) _ Josh Heupel set school records with five touchdown passes and 31 completions Saturday night as Oklahoma beat Indiana State 49-0 to give Bob Stoops a resounding victory in his debut as head coach.

Heupel, a junior-college transfer, was 31-of-40 for 341 yards and an interception. He eclipsed Cale Gundy's record of 25 completions set in 1991 against Virginia, and his five TDs were one more than the mark held by three players.

The 341 yards tied Gundy's school record set against Texas Tech in 1992.

Indiana State, a Division I-AA school, is 0-2 and has been outscored 82-7. The Sycamores became Oklahoma's first shutout victim since 1993.

Heupel, a left-hander, did a nice job directing Oklahoma's new controlled passing game. He completed passes to 12 players and found a different receiver with each touchdown.

Heupel threw touchdown passes of 19, 6 and 5 yards as Oklahoma took a 28-0 lead at halftime. He was 6-of-9 for 81 yards on Oklahoma's first scoring drive, which covered 92 yards, capping it with a 19-yard touchdown pass to Andre Woolfolk.

Michael Thornton, who led Oklahoma with 85 yards rushing on 19 carries, had a 10-yard TD run late in the first quarter. Heupel followed with short touchdown passes to Josh Norman and Jarrail Jackson in the second quarter.

Heupel was 6-for-6 for 60 yards on the Sooners' first drive after halftime, which he finished off with an 11-yard TD pass to Julius McMillan. His final TD pass was his longest, a 33-yarder to walk-on Ryan Daniel early in the fourth quarter.

Indiana State's option offense gained 41 yards on the first possession, but the Sycamores had only 93 the rest of the half and were outgained 507-195.

The Sooners are coming off the worst three-year stretch in school history, 12-22 under John Blake. Stoops has vowed there will be no excuses for Oklahoma's play and that his team would cut down on mental mistakes that have been costly in recent years.

Oklahoma lost three fumbles and Heupel was intercepted, but the Sooners were penalized just once. A year ago, they had as many as 19 in a game; their lowest total was six, twice.

The 47 points were the most scored by Oklahoma since a 51-10 victory over North Texas in the third game of 1995.